Hereditary spastic ataxia with congenital miosis: four cases in one family.

Hereditary spastic ataxia with congenital miosis: four cases in one family.

A family with hereditary ataxia.

An Indian family with four members having hereditary ataxia was presented. The inheritance was most likely autosomal dominant. The onset was at adult life. The main disability was cerebellar ataxia with pyramidal tract sign found at physical examination. Electroencephalography and nerve conduction study were abnormal in two cases where they were done. The clinical feature correspond to an inter...

Hereditary Spastic Ataxia Simulating Disseminated Sclerosis.

In 1929 Ferguson and Critchley published a detailed clinical study of a family, many members of which suffered from a disease resembling disseminated sclerosis. As far as Ferguson and Critchley could discover the syndrome described had not been recorded previously. The average age of onset was 35 to 45 years and the initial symptoms were weakness and unsteadiness of the legs, followed by dysart...

Hereditary benign Telangiectasia: Report of 6 cases in a family

Hereditary benign telangiectasia is an uncommon idiopathic skin disorder characterized by generalized telangiectases and angiomatous lesions of the skin. The diagnosis should be suspected in patients with such cutaneous lesions, positive family history, no associated bleeding problems, and no mucosal involvement. We present six cases of hereditary benign telangiectasia in three generations of o...

Hereditary spastic paraplegia and hereditary ataxia, Part 2: A family demonstrating various phenotypic manifestations with the SCA3 genotype.

BACKGROUND Clinical descriptions of the dominantly inherited ataxic motor syndromes in a 7-generation family of German origin were first reported in 1951. OBJECTIVE To provide follow-up clinical, pathological, and genetic data for 9 patients in this family. DESIGN Clinical histories and neurologic findings, gross and microscopic pathological features, and DNA analysis. RESULTS Clinical pr...